The Bias That Ruins So Much Science

Peloni:  Science, good science, requires a concerted effort to design studies to specifically remove factors such as selection bias, and yet, what we have seen over the past several years, particularly in what has been passed as ‘research’ on Covid and the ‘safe and effective’ vaccines, is an almost routine use of such mismanaged study designs whose results are dependent upon those factors not being considered and not being removed.  Bad science is in fact not science at all.  It is propaganda, commonly used to mask its support for special interests as was true going back to the Bernay survey which came to recommend the import of eating bacon for breakfast to improve the sales of the pork industry over a century ago.  As the Covid scam becomes more and more revealed and its foundational scientific research is demonstrably seen to be not just flawed but rigged towards an ultimate outcome, demand an accountability for all who were involved in this skullduggery, and a return to investigating the wonders of the universe asnd not the profit margins of such industries as are supported by selection bias passed off as scientific research.

Jeffrey A. Tucker | July 3, 2024

These last years have provided a tremendous education in the ways seemingly rigorous science can actually be highly misleading. Much of the problem traces to a simple idea: selection bias. Once you understand it, much of what we think we know about what is true, along with many studies showing it to be true, melt away.

Good science corrects for the problem but it is still ubiquitous.

Let’s take a simple example.

Say you have a dog and you make his own meals. You are careful about this and rather strict, making sure that you have all the right vitamins and minerals in the meals and each is the right size and you stick with it daily. You monitor the results. You save money. The dog is healthy and happy.

But then someone comes along waving scientific literature on the topic. They point out that all the studies show that dogs fed with home-cooked meals have a far higher rate of gastrointestinal problems. In fact many studies show this, and veterinarians cite them in defense of commercial dog food.

They yell at you: Never feed dogs people food. It will make them sick. The only real path to a healthy pet is the bags at the store.

It’s intimidating, isn’t it? You think you are doing the right thing but the experts say otherwise. What might be going on? Well, the science is not wholly incorrect. It is likely true that dogs who are fed with commercial food are generally healthier than those who eat table scraps.

Why might that be? Simple. The subjects who buy the commercial stuff tend to be more scrupulous about their pet’s health. They measure. They feed at certain times per day. With a stable commercial product, there is less to go wrong. They are willing to spend more money on pet food.

On the other hand, people who report feeding dogs people food are more likely the neglectful ones, scraping the leftovers into the dog’s bowl and otherwise giving the dog whatever scraps fall from the table. Could be tacos, mac and cheese, salad with dressing, or a big piece of meat with sauces and salts and whatever. They simply are not monitoring.

And sure enough, those people end up with pets at the doctor more often. That is precisely when the gastrointestinal problems are found and recorded.

That’s not what you do, but you are lumped into the others in the selection bias. The truth might be the opposite of the study. The people who make stable and healthy meals for their pets are doing better for the dog’s health than those who use commercial food filled with grains and processed products. But you are not the sample being studied.

The study’s conclusions, then, are reversed by the problem of the built-in bias. In other words, the study was designed to produce the precise results that it did produce.

This is a major feature of so many scientific undertakings. They generalize from a population that includes a range of behaviors but it is dominated by one feature and conclude fallacious recommendations from the whole.

Consider the example of red-wine studies from years ago. They concluded that drinking one or two glasses of red wine per day can be good for the heart. They deduced this based on surveys that showed precisely that: People who drink red wine daily have fewer overall health problems than those who do not.

It took many years but finally some researchers grew suspicious. They wondered if the study was a victim of selection bias. Perhaps moderate drinkers were healthier than non-drinkers, because they were from a higher socioeconomic status. They are wealthy and physically active. They are more likely to have health insurance, see doctors more often, and eat balanced diets. And they had another theory: the non-drinkers in the study might in fact be ex-drinkers who quit to stop health decline.

Sure enough, after reviewing more than a hundred studies, researchers have more recently concluded that no amount of alcohol is good for you and that studies that say the opposite were making conclusions about causation that could not be supported by the studies’ results. Now, we find that the conventional wisdom has shifted again. It took decades but now we are seeing that the studies were flawed from the beginning.

This is what shoddy science does. It makes us believe one thing that turns out not to be true once the selection bias is eliminated.

This problem has been huge for vaccine studies over the last three years. The question was a simple one. Among the populations that received the initial round plus boosters, against those who received neither, which had the fewer health problems? You might think that constructing such a study would be simple.

It is not simple because you must compare likes to likes. You cannot compare relatively unhealthy populations to relatively less healthy populations. That would make a mess of the conclusions of the question you are trying to answer. But it turns out that this is precisely what many studies did. They committed the error of building in a “healthy vaccinee bias.”

As you might expect, the people who complied with the mandates and then got boosters tended to be of higher socioeconomic status, have health insurance, visit the doctor more often, and are generally more scrupulous about their health. The people who never got one might have done so because they didn’t trust the vaccine, but they also might not have had access to quality health care and generally disregard their health.

The crucial point here is that even a small bias can ruin such a study. As it turns out, this is precisely what happened in most early studies. As time went on, more researchers got involved in looking more carefully. They discovered that once you eliminate the basis, the conclusions of the study are not only not supported but sometimes even reversed. This is especially true because more people grew suspicious over time, such that healthier populations started to say no.

In order to discover the healthy vaccinee bias, one only needs to discover that the people who received the vaccine were generally more healthy than those who did not. Further, one needs to discover that researchers did not account for that. That is precisely what several Czech researchers found earlier this year from looking at millions of health records in studies.

They conclude: “Consistently over datasets and age categories, all cause mortality (ACM) was substantially lower in the vaccinated than unvaccinated groups regardless of the presence or absence of a wave of COVID-19 deaths. Moreover, the ACMs in groups more than 4 weeks from Doses 1, 2, or 3 were consistently several times higher than in those less than 4 weeks from the respective dose. The healthy vaccinee effect appears to be the only plausible explanation for this, which is further corroborated by a created mathematical model.”

That is a serious and substantial error. It causes the judgments to be reversed. What seems to be science is actually rooted in what is really a simple mistake. Sadly, this selection bias is a huge factor in many studies. Once you become aware of it, you can spot it rather quickly.

Let’s say a study appears today that says people who eat roasted brussel sprouts tend to live longer, healthier, and richer lives. Are you going to believe that the brussel sprouts cause this to happen or will you now clearly see that what is being tested here is a feature of the selection rather than an underlying cause?

Remember this: A life lived according to the dictates of “the science” puts your life decisions at the mercy of the integrity of the researchers. That might not be the wisest choice.

Views expressed in this article are opinions of the author and do not necessarily reflect the views of The Epoch Times.

July 4, 2024 | 1 Comment »

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  1. Smoking saved my life. Here’s how. I was a chain smoker from 1979 until I stopped in 2007. About 10 years later, I was feeling some pressure in my chest after exertion and I recalled that Yul Brynner had made a commercial before his death in which he said that he got lung cancer 15 years after he quit! So, I asked the doctor to have an exam, and I didn’t have lung cancer, just a little bit of scarring on my lungs, but it turned out I had a condition the doctors had never seen before! One had seen it in children. An artery was pressing on my windpipe and cutting off my air.* So, I had surgery. It’s doing it again, but now the windpipe has developed rings and is fighting back. Like Israel needs to do from now on. No more mowing the lawn.

    😀

    (alternate line: I was a chain smoker until I discovered tobacco tasted better than chains. 😀 )

    Great article, though. All of that flipping back and forth made me mistrust medical science that predicts likely outcomes. Funny, how I didn’t hesitate to take the vaccine when it first came out. Well, I have a cousin who is a scientist and she said, “do you never want to go outside again?”

    Now a new generation is coming of age that goes, “there was a pandemic?” 😀

    Like America after the one in the ’20s and the one Daniel Greenfield writes about that took place at the beginning of the 19th century that was also manipipulated by the left for political control.

    Great article!
    *
    Of course, now when I feel pressure in my chest, I know it’s probably my ulcers in my duodenum and esophagus aggravated by GERD (gastrointestinal reflux disease) so even pat or past explanations of phenomena which fit all the symptoms could wind up being something else. After my surgery, they mistakenly misdiagnosed my abdominal distress as atrial phibrilation (which I did have another time while being examined by a doctor, hence the blood thinner I’m on) when I had knee replacement surgery, and they put me in the cardiac wing for observation for a week instead of the knee recuperation wing which extended my agonizing recoverty (2 or 3 months.)

    Science isn’t great but it’s better than it used to be. I remember – in the ’80s – lying on the floor moaning and saying I’ll just lie here until I get better until my room-mates nagged me sufficiently to go the ER and after waiting all night behind gunshot victims – the reason I was never picked for a criminal trial on jury duty like 99 percent of the rest of every jury pool in Manhattan 😀 ) the doctor saw me for 2 or 3 minutes and wrote out a prescription for Robitusson. 😀

    The comedic high point of my double hernia surgery in the 90s was the elderly chiel surgeon telling his student with the knife – the regional anesthesia didn’t work – “No, No, a little more to the left.” 😀

    Cheers.

    I remember an Asian-American violinist I worked with many years ago who said he would have preferred to live at the beginning of the 20th century and gettting a little miffed when I demurred, “sure, except for the racism and the bad medicine.” 😀